SNP Report

Basic Info

Name	rs10275045 dbSNP Ensembl
Location	chr7:1881190 - 1881190(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.358427
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000265854, ENST00000399654, ENST00000402746, ENST00000406869, ENST00000450235)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Ruderfer, D. M., 2013			P-value=2.08E-04 for BP, P-value=2.22E-09 for BP+SZ, Het P-v...... P-value=2.08E-04 for BP, P-value=2.22E-09 for BP+SZ, Het P-value=0.35 More...	Most significant SNP in six genome-wide significant regions....... Most significant SNP in six genome-wide significant regions. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	7p22	5(1/2/2)

SNPs in LD with rs10275045 (count: 0) View in gBrowse (chr7:1881190..1881190 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Ruderfer, D. M., 2013	P-value=1.84E-06 for BP, P-value=5.53E-13 for BP+SZ, Het P-value=0.85	Most significant SNP in six genome-wide significant regions.	Negative

Overlap with MDD from cross-disorder studies (count: 0)