SNP Report

Basic Info

Name	rs135745 dbSNP Ensembl
Location	chr22:38287631 - 38287631(1)
Variant Alleles	G/C
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.407149
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000359867, ENST00000366216, ENST00000396832, ENST00000400206, ENST00000431632)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Matsunaga, S.,2012	C/G		Chi square test:MAF = 0.25,P-value = 0.39,OR = 1.06 Chi square test:MAF = 0.25,P-value = 0.39,OR = 1.06	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CSNK1E	casein kinase 1, epsilon	22q13.1	5(1/3/1)

SNPs in LD with rs135745 (count: 0) View in gBrowse (chr22:38287631..38287631 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Matsunaga, S.,2012	Chi square test:MAF = 0.26,P-value = 0.12,OR = 1.12;P-value = 0.095,OR = 1.26in meta analysis	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Matsunaga, S.,2012	Chi square test:MAF = 0.21,P-value = 0.08,OR = 0.85	No significant association was observed.	Negative