SNP Report

Basic Info
Name rs11150863 dbSNP Ensembl
Location chr17:80558521 - 80558521(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.285743
Functional Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000306801, ENST00000544334, ENST00000570891, ENST00000573746, ENST00000574767, ENST00000577161); NMD_transcript_variant(ENST00000574767); non_coding_transcript_variant(ENST00000573746, ENST00000577161)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Bergen, S. E.,2012 A logistic regression: P-value > E-05 logistic regression: P-value > E-05 No significant association was observed in BD. No significant association was observed in BD. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
NPTX1 neuronal pentraxin I 17q25.3 2(1/1/0)
RPTOR regulatory associated protein of MTOR, complex 1 17q25.3 2(1/1/0)

SNPs in LD with rs11150863 (count: 30) View in gBrowse (chr17:80541410..80730099 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 30)

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Bergen, S. E.,2012 logistic regression:for SZ new sample, OR=0.78, P-value = 3.49E-06 No significant association was observed in SZ. Negative

Overlap with MDD from cross-disorder studies (count: 0)