SNP Report

Basic Info

Name	rs2337506 dbSNP Ensembl
Location	chrCHR_HSCHR15_4_CTG8:32204709 - 32204709(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.476038
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000306901, ENST00000437966, ENST00000454250, ENST00000635722, ENST00000635759, ENST00000635884, ENST00000635978, ENST00000636044, ENST00000636271, ENST00000636295, ENST00000636440, ENST00000636603, ENST00000636647, ENST00000636850, ENST00000637033, ENST00000637183, ENST00000637350, ENST00000637519, ENST00000637552, ENST00000637786, ENST00000637971, ENST00000638031, ENST00000638106); NMD_transcript_variant(ENST00000437966, ENST00000635722, ENST00000635759, ENST00000636044, ENST00000636271, ENST00000636850, ENST00000637350, ENST00000637519, ENST00000637786, ENST00000637971, ENST00000638031); non_coding_transcript_variant(ENST00000636295, ENST00000636647, ENST00000455693)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Joo, E. J.,2010	A/G		Association analysis: allele P-value > 0.05, genotype P-valu...... Association analysis: allele P-value > 0.05, genotype P-value > 0.05 More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CHRNA7	cholinergic receptor, nicotinic, alpha 7 (neuronal)	15q13.3	4(2/2/0)

SNPs in LD with rs2337506 (count: 0) View in gBrowse (chrCHR_HSCHR15_4_CTG8:32204709..32204709 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Joo, E. J.,2010	Association analysis:allele P-value > 0.05, genotype P-value > 0.05	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)