BDgene

Gene Report

Basic Info
Approved Symbol CACNG5
Approved Name calcium channel, voltage-dependent, gamma subunit 5
Location 17q24
Position chr17:66835117-66885486, 1
External Links HGNC: 1409
Entrez Gene: 27091
Ensembl: ENSG00000075429
UCSC: uc010wqj.2
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Jan, W. C., 2014 SNP: rs2286677 No marker in this gene was found to the significant. Negative Comment on Study
Curtis, D.,2011 SNP: rs17645023 The application of this approach suggests that it does have some merits. The finding for CACNG5, taken together with the earlier implication of CACNA1C and CACNA1B, strongly suggests a key role for voltage-dependent calcium channel genes in the susceptibility to bipolar disorder and/or schizophrenia. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 9)

GO terms by PBA (count: 2)

GO terms by database search (count: 7)


Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)


Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 6)

Literature-origin SNPs (count: 2)

LD-proxies (count: 4)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)


Gene relationship with MDD

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Region: chr17:66835117..66885486 View in gBrowse
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