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SNP Report
Name | rs1051168 dbSNP Ensembl | ||
---|---|---|---|
Location | chr15:84657289 - 84657289(1) | ||
Variant Alleles | G/T | ||
Ancestral Allele | G | ||
Minor Allele | T | ||
Minor Allele Frequence | 0.138379 | ||
Functional Annotation | missense_variant; upstream_gene_variant.
Polyphen Annotation: possibly damaging(ENST00000394588); benign(ENST00000360476) SIFT Annotation: tolerated(ENST00000360476, ENST00000394588) |
||
Consequence to Transcript | missense_variant(ENST00000360476, ENST00000394588); upstream_gene_variant(ENST00000398528, ENST00000434634, ENST00000558019, ENST00000558487, ENST00000558521, ENST00000559015, ENST00000559126, ENST00000559178, ENST00000559224, ENST00000559452, ENST00000559877, ENST00000559994, ENST00000560088, ENST00000560182, ENST00000560252, ENST00000560835, ENST00000560966, ENST00000561329, ENST00000561434, ENST00000561447) | ||
No. of Studies | 1 (Positive: 1; Negative: 0; Trend: 0) | ||
Source | Literature | ||
Overlap with SZ? | YES | ||
Overlap with MDD? | NO |
Reference | Statistical Result | Description | Result Category |
---|---|---|---|
Andreassen OA, 2013 | Conditional FDR; SCZ loci given BD: P-value=0.000127, FDR=0.203, FDR=0.033 for SCZ and BD | To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. | Positive |