SNP Report

Basic Info

Name	rs127503 dbSNP Ensembl
Location	chr6:108158429 - 108158429(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.42512
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000426008); intron_variant(ENST00000440575, ENST00000492070); non_coding_transcript_exon_variant(ENST00000441184); non_coding_transcript_variant(ENST00000441184, ENST00000492070)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kumar, R. A., 2008	G/A		X²=1.66, OR (95% CI)=0.87 (0.71-1.08), P-value = ...... X²=1.66, OR (95% CI)=0.87 (0.71-1.08), P-value = 0.198 for bipolar disorder (I and II combined). X²=1.88, OR (95% CI)=0.86 (0.69-1.07), P-value = 0.170 for bipolar I disorder. X²=0.00, OR (95% CI)=1.01 (0.56-1.82), P-value = 0.972 for bipolar II disorder. More...		Negative

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NR2E1	nuclear receptor subfamily 2, group E, member 1	6q21	1(1/0/0)
OSTM1-AS1	OSTM1 antisense RNA 1	6q21	Mapped by Literature SNP
OSTM1	osteopetrosis associated transmembrane protein 1	6q21	Mapped by Literature SNP

SNPs in LD with rs127503 (count: 0) View in gBrowse (chr6:108158429..108158429 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Kumar, R. A., 2008	X²=0.51, OR (95% CI)=0.93 (0.93-1.15), P-value = 0.475 for SZ.	No association was detected with schizophrenia.	Negative

Overlap with MDD from cross-disorder studies (count: 0)