SNP Report

Basic Info

Name	rs2280468 dbSNP Ensembl
Location	chr15:88838325 - 88838325(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.342252
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000352105, ENST00000439576, ENST00000558207, ENST00000559004, ENST00000561243, ENST00000617301)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McAuley, E. Z., 2012	A/G		P-value = 0.031, Empirical P-value = 0.03, OR (95% CI)=0.70 ...... P-value = 0.031, Empirical P-value = 0.03, OR (95% CI)=0.70 (0.51-0.96) in the Australian bipolar disorder cohort More...	Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. Association with 14 of these SNPs held true when empirical P values were obtained through 10, 000 replicate permutations. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ACAN	aggrecan	15q26.1	1(1/0/0)

SNPs in LD with rs2280468 (count: 0) View in gBrowse (chr15:88838325..88838325 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
McAuley, E. Z., 2012	P-value > 0.075	Single SNP analysis did not yield significant evidence for association.	Negative

Overlap with MDD from cross-disorder studies (count: 0)