SNP Report

Basic Info

Name	rs1487141 dbSNP Ensembl
Location	chr8:32282136 - 32282136(1)
Variant Alleles	G/C
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.251597
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000517967, ENST00000518104, ENST00000519301, ENST00000520407, ENST00000523320, ENST00000523534, ENST00000631040); non_coding_transcript_variant(ENST00000517967, ENST00000523320)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Thomson, P. A., 2007			Individual P-value = 0.7254 for BP, Individual P-value = 0.8...... Individual P-value = 0.7254 for BP, Individual P-value = 0.8195 for SCZ and BP More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs1487141 (count: 8) View in gBrowse (chr8:32280094..32307171 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs1487142	intron_variant; non_coding_transcript_variant	1.0[CEU]; 0.941[TSI]
rs6468095	intron_variant	0.888[TSI]
rs7836407	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[TSI]
rs10503904	intron_variant	0.878[TSI]
rs17630934	intron_variant	0.879[TSI]
rs16879111	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs1872798	downstream_gene_variant; intron_variant	1.0[CEU]
rs4733117	intron_variant; non_coding_transcript_variant	0.923[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A., 2007	Individual P-value = 0.9662 for SCZ , Individual P-value = 0.8195 for SCZ and BP		Negative

Overlap with MDD from cross-disorder studies (count: 0)