SNP Report

Basic Info

Name	rs7083127 dbSNP Ensembl
Location	chr10:18342516 - 18342516(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.292931
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000282343, ENST00000324631, ENST00000352115, ENST00000377319, ENST00000377328, ENST00000377329, ENST00000377331, ENST00000396576, ENST00000498816, ENST00000612134, ENST00000612743, ENST00000615785, ENST00000617363); non_coding_transcript_variant(ENST00000498816)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Andreassen OA, 2013			Conditional FDR; BD loci given SCZ: P-value=0.00014, FDR=0.3...... Conditional FDR; BD loci given SCZ: P-value=0.00014, FDR=0.37364, FDR=0.02191 for BD and SCZ More...	This SNP is with conditional FDR<0.05 in schizophrenia given...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CACNB2	calcium channel, voltage-dependent, beta 2 subunit	10p12	3(2/1/0)

SNPs in LD with rs7083127 (count: 0) View in gBrowse (chr10:18342516..18342516 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Andreassen OA, 2013	Conditional FDR; BD loci given SCZ: FDR=0.02191 for BD and SCZ	This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'.	Positive

Overlap with MDD from cross-disorder studies (count: 0)