SNP Report

Basic Info

Name	rs113317778 dbSNP Ensembl
Location	chr8:31640156 - 31640156(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.127196
Functional Annotation	intron_variant; missense_variant; upstream_gene_variant. Polyphen Annotation: unknown(ENST00000520407, ENST00000614767) SIFT Annotation: deleterious - low confidence(ENST00000520407, ENST00000614767)
Consequence to Transcript	intron_variant(ENST00000518104, ENST00000519301); missense_variant(ENST00000520407, ENST00000614767); upstream_gene_variant(ENST00000523534)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Gutierrez-Fernandez, A., 2014			P-value=0.0187 P-value=0.0187	Several allelic associations were found in the entire pool o...... Several allelic associations were found in the entire pool of BD. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs113317778 (count: 0) View in gBrowse (chr8:31640156..31640156 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Gutierrez-Fernandez, A., 2014		Several allelic associations were found in the entire pool of BD, but not in schizophrenia.	Negative

Overlap with MDD from cross-disorder studies (count: 0)