BDgene

SNP Report

Basic Info
Name rs3858917 dbSNP Ensembl
Location chr15:92428581 - 92428581(1)
Variant Alleles T/G
Ancestral Allele T
Minor Allele G
Minor Allele Frequence 0.45627
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000268164, ENST00000539113, ENST00000555434)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
McAuley, E. Z., 2012 C/A P-value = 0.046, Empirical P-value = 0.055, OR (95% CI)=0.74...... P-value = 0.046, Empirical P-value = 0.055, OR (95% CI)=0.74 (0.56-0.99) in the Australian bipolar disorder cohort More... Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 15q26 2(2/0/0)

SNPs in LD with rs3858917 (count: 17) View in gBrowse (chr15:92411086..92436217 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 17)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
McAuley, E. Z., 2012 P-value > 0.075 Single SNP analysis did not yield significant evidence for association. Negative

Overlap with MDD from cross-disorder studies (count: 0)