SNP Report

Basic Info

Name	rs2117975 dbSNP Ensembl
Location	chr15:39865113 - 39865113(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.108626
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000299092, ENST00000558041, ENST00000560729, ENST00000561100); non_coding_transcript_variant(ENST00000558041, ENST00000560729)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Huang, J.,2010	A/G		Omnibus GWAS Test: P-value > 5E-05 Omnibus GWAS Test: P-value > 5E-05	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GPR176	G protein-coupled receptor 176	15q14-q15.1	Mapped by Literature SNP
EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4	15q13.3	1(0/1/0)

SNPs in LD with rs2117975 (count: 0) View in gBrowse (chr15:39865113..39865113 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Huang, J.,2010	Omnibus GWAS Test:P-value = 0.000037, best-fit model is Schizophrenia specific	Suggestive association was found.	Trend

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Huang, J.,2010	Omnibus GWAS Test:P-value > 5E-05	No significant association was observed.	Negative