SNP Report

Basic Info

Name	rs10277665 dbSNP Ensembl
Location	chr7:11519953 - 11519953(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.201877
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000423059, ENST00000445839, ENST00000497575, ENST00000617773); non_coding_transcript_variant(ENST00000445839, ENST00000497575)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Andreassen OA, 2013			Conditional FDR; BD loci given SCZ: P-value=0.0000542, FDR=0...... Conditional FDR; BD loci given SCZ: P-value=0.0000542, FDR=0.24328, FDR=0.01641 for BD and SCZ More...	This SNP is with conditional FDR<0.05 in schizophrenia given...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
THSD7A	thrombospondin, type I, domain containing 7A	7p21.3	1(1/0/0)

SNPs in LD with rs10277665 (count: 0) View in gBrowse (chr7:11519953..11519953 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Andreassen OA, 2013	Conditional FDR; BD loci given SCZ: FDR=0.01641 for BD and SCZ	This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'.	Positive

Overlap with MDD from cross-disorder studies (count: 0)