SNP Report

Basic Info
Name |
rs946903
dbSNP
Ensembl
|
Location |
chr1:147625465 - 147625465(1) |
Variant Alleles |
T/C |
Ancestral Allele |
T |
Minor Allele |
C |
Minor Allele Frequence |
0.304313 |
Functional Annotation |
3_prime_UTR_variant; downstream_gene_variant.
|
Consequence to Transcript |
3_prime_UTR_variant(ENST00000234739); downstream_gene_variant(ENST00000609196) |
No. of Studies |
1 (Positive: 0; Negative: 1; Trend: 0) |
Source |
Literature |
Overlap with SZ? |
YES
|
Overlap with MDD? |
YES
|

SNP related studies (count: 1)

SNP related genes (count: 2)
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 6)

rs_ID |
Literature-origin SNPs with LD |
Functional Annotation |
r2[population] |
rs12409268
|
|
intron_variant |
0.951[JPT]
|
rs6675828
|
|
downstream_gene_variant; intron_variant; non_coding_transcript_variant |
0.808[CHB]; 0.803[CHD]; 0.907[JPT]
|
rs7512513
|
|
downstream_gene_variant; intron_variant; non_coding_transcript_variant |
0.878[CHB]; 0.812[CHD]; 0.907[JPT]
|
rs12132534
|
|
downstream_gene_variant |
0.877[CHB]; 0.905[JPT]
|
rs12122799
|
|
intron_variant; non_coding_transcript_variant; upstream_gene_variant |
0.803[CHD]; 0.907[JPT]
|
rs17160476
|
|
intron_variant |
0.873[CHB]; 0.907[JPT]
|

Overlap with SZ from cross-disorder studies (count: 1)
Reference |
Statistical Result |
Description |
Result Category |
Li, J.,2011(b) |
Third-Stage Sample:for SZ, allele association P-value = 0.47, OR(95%CI)=0.95(0.83-1.10);Combined Third-Stage Sample, allele association P-value = 0.16, OR(98%CI)=0.95(0.89-1.02) |
No significant association was observed. |
Negative |

Overlap with MDD from cross-disorder studies (count: 1)
Reference |
Statistical Result |
Description |
Result Category |
Li, J.,2011(b) |
Third-Stage Sample:for MDD, allele association P-value = 0.006, OR(95%CI)=0.82(0.71-0.95) |
Significant association was observed in MDD. |
Positive
|