SNP Report

Basic Info

Name	rs2304674 dbSNP Ensembl
Location	chr2:238273263 - 238273263(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.348642
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000431832); intron_variant(ENST00000254657, ENST00000355768); non_coding_transcript_variant(ENST00000355768)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mansour, H. A.,2009	A/G		Single SNP-based analyses: Trends test P-value = 0.051 in BP...... Single SNP-based analyses: Trends test P-value = 0.051 in BPI More...	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PER2	period circadian clock 2	2q37.3	7(1/6/0)

SNPs in LD with rs2304674 (count: 6) View in gBrowse (chr2:238267745..238293490 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs3739064	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.83[CEU]
rs1972874	intron_variant; non_coding_transcript_variant	0.844[CEU]
rs6754875	intron_variant; upstream_gene_variant	0.885[CEU]; 0.945[TSI]
rs11892309	intron_variant; upstream_gene_variant	0.885[CEU]; 0.945[TSI]
rs13002160	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.885[CEU]; 0.919[TSI]
rs11892306	intron_variant; upstream_gene_variant	0.885[CEU]; 0.945[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Mansour, H. A.,2009	Single SNP-based analyses:Trends test P-value = 0.033 in SZ	Significant association was observed	Positive

Overlap with MDD from cross-disorder studies (count: 0)