BDgene

SNP Report

Basic Info
Name rs7341475 dbSNP Ensembl
Location chr7:103764368 - 103764368(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.148762
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000343529, ENST00000424685, ENST00000428762)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Pisante, A.,2009 G two-tail X2 test: GG genotype, P-value > 0.05 two-tail X2 test: GG genotype, P-value > 0.05 No significant association was observed in BD. No significant association was observed in BD. Negative
Goes, F. S., 2010 TDT test: P-value = 0.38 for all samples and P-value = 0.46 ...... TDT test: P-value = 0.38 for all samples and P-value = 0.46 for female-stratified sample. More... no evidence for transmission disequilibrium for rs7341475 no evidence for transmission disequilibrium for rs7341475 Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
RELN reelin 7q22 3(1/2/0)

SNPs in LD with rs7341475 (count: 0) View in gBrowse (chr7:103764368..103764368 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Pisante, A.,2009 two-tail X2 test:GG genotype, P-value = 0.035 for females A significant effect was only seen in females. Positive

Overlap with MDD from cross-disorder studies (count: 0)