SNP Report

Basic Info

Name	rs7341475 dbSNP Ensembl
Location	chr7:103764368 - 103764368(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.148762
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000343529, ENST00000424685, ENST00000428762)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pisante, A.,2009		G	two-tail X² test: GG genotype, P-value > 0.05 two-tail X² test: GG genotype, P-value > 0.05	No significant association was observed in BD. No significant association was observed in BD.	Negative
Goes, F. S., 2010			TDT test: P-value = 0.38 for all samples and P-value = 0.46 ...... TDT test: P-value = 0.38 for all samples and P-value = 0.46 for female-stratified sample. More...	no evidence for transmission disequilibrium for rs7341475 no evidence for transmission disequilibrium for rs7341475	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
RELN	reelin	7q22	3(1/2/0)

SNPs in LD with rs7341475 (count: 0) View in gBrowse (chr7:103764368..103764368 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Pisante, A.,2009	two-tail X² test:GG genotype, P-value = 0.035 for females	A significant effect was only seen in females.	Positive

Overlap with MDD from cross-disorder studies (count: 0)