SNP Report
Basic Info
Name |
rs1480380
dbSNP
Ensembl
|
Location |
chrCHR_HSCHR6_MHC_SSTO_CTG1:33036169 - 33036169(1) |
Variant Alleles |
C/T |
Ancestral Allele |
T |
Minor Allele |
T |
Minor Allele Frequence |
0.0826677 |
Functional Annotation |
downstream_gene_variant; intron_variant; upstream_gene_variant.
|
Consequence to Transcript |
downstream_gene_variant(ENST00000374843, ENST00000395303, ENST00000395305, ENST00000422832, ENST00000456800, ENST00000464392, ENST00000475627, ENST00000477541, ENST00000480785); intron_variant(ENST00000429234); upstream_gene_variant(ENST00000418107, ENST00000498020, ENST00000433630, ENST00000434337, ENST00000437285, ENST00000451753, ENST00000452330, ENST00000466040, ENST00000477135, ENST00000479036, ENST00000479386, ENST00000490859, ENST00000435056, ENST00000395312, ENST00000413617, ENST00000480557, ENST00000416297, ENST00000422196, ENST00000451148, ENST00000452703, ENST00000453490, ENST00000460128, ENST00000466446, ENST00000475284, ENST00000481354, ENST00000493659, ENST00000430099, ENST00000418759, ENST00000424822, ENST00000466737, ENST00000420931, ENST00000439054, ENST00000441171, ENST00000443447, ENST00000456486, ENST00000465136, ENST00000467732, ENST00000470656, ENST00000472231, ENST00000487750, ENST00000449679, ENST00000440078, ENST00000447454, ENST00000461570, ENST00000420299, ENST00000426176, ENST00000432991, ENST00000440717, ENST00000452615, ENST00000475844, ENST00000485999, ENST00000489001, ENST00000494230, ENST00000495512, ENST00000415927, ENST00000428420, ENST00000452407, ENST00000487546, ENST00000416806, ENST00000419041, ENST00000419231, ENST00000441375, ENST00000457285, ENST00000462225, ENST00000469705, ENST00000472833, ENST00000487786, ENST00000489879, ENST00000448590, ENST00000450897, ENST00000456428, ENST00000482267, ENST00000435503, ENST00000450601, ENST00000452434, ENST00000454298, ENST00000458066, ENST00000466043, ENST00000469049, ENST00000472934, ENST00000479292, ENST00000491978, ENST00000415090, ENST00000383231, ENST00000428864, ENST00000463532, ENST00000383227, ENST00000383228, ENST00000383230, ENST00000412394, ENST00000418042, ENST00000461059, ENST00000466370, ENST00000477208, ENST00000486785, ENST00000498081, ENST00000449417, ENST00000412948, ENST00000439344, ENST00000476119) |
No. of Studies |
1 (Positive: 1; Negative: 0; Trend: 0) |
Source |
Literature |
Overlap with SZ? |
YES
|
Overlap with MDD? |
NO
|
SNP related studies (count: 1)
SNP related genes (count: 2)
Overlap with SZ from cross-disorder studies (count: 1)
Reference |
Statistical Result |
Description |
Result Category |
Andreassen OA, 2013 |
Conditional FDR; SCZ loci given BD: P-value=0.0000106, FDR=0.077, FDR=0.01 for SCZ and BD |
To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. |
Positive |
Overlap with MDD from cross-disorder studies (count: 0)