Gene Report

Basic Info
Approved Symbol FABP3
Previous Symbol MDGI, FABP11
Symbol Alias H-FABP, O-FABP
Approved Name fatty acid binding protein 3, muscle and heart
Previous Name fatty acid binding protein 11, "fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)"
Name Alias mammary-derived growth inhibitor
Location 1p33-p32
Position chr1:31365625-31376850, -1
External Links HGNC: 3557
Entrez Gene: 2170
Ensembl: ENSG00000121769
UCSC: uc001bss.1
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Moskvina, V.,2009 In BP:Smallest P-value per gene=0.01657, Product of P truncation <=0.01=0.00075, Product of P truncation <=0.001=NA. It showed evidence for association with BD. Positive Comment on Study
Iwayama, Y., 2010 SNP: rs10914367, rs11436, rs12562824, rs3766293, rs3795432, rs6425744, rs6663779, rs7532813 FABP3 displayed no association with bipolar disorder. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 20)

GO terms by PBA (count: 1)

GO terms by database search (count: 19)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 18)

Literature-origin SNPs (count: 8)

LD-proxies (count: 10)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 2)

Overlap with SZ from candidate gene intersection analysis (count: 2)

Gene relationship with MDD

View in gBrowse

Region: chr1:31365625..31376850 View in gBrowse
View in gBrowse