SNP Report

Basic Info

Name	rs2640909 dbSNP Ensembl
Location	chr1:7830057 - 7830057(1)
Variant Alleles	T/C
Minor Allele	C
Minor Allele Frequence	0.185304
Functional Annotation	missense_variant; upstream_gene_variant. Polyphen Annotation: benign(ENST00000614998, ENST00000361923, ENST00000377532, ENST00000613533) SIFT Annotation: tolerated - low confidence(ENST00000361923, ENST00000377532, ENST00000613533); tolerated(ENST00000614998)
Consequence to Transcript	missense_variant(ENST00000614998, ENST00000361923, ENST00000377532, ENST00000613533); upstream_gene_variant(ENST00000451646)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mansour, H. A.,2009			Single SNP-based analyses: Trends test P-value = 0.421 in BP...... Single SNP-based analyses: Trends test P-value = 0.421 in BPI More...	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PER3	period circadian clock 3	1p36.23	7(3/4/0)

SNPs in LD with rs2640909 (count: 0) View in gBrowse (chr1:7830057..7830057 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Mansour, H. A.,2009	Single SNP-based analyses:Trends test P-value = 0.031 in SZ	Significant association was observed	Positive

Overlap with MDD from cross-disorder studies (count: 0)