BDgene

SNP Report

Basic Info
Name rs2640909 dbSNP Ensembl
Location chr1:7830057 - 7830057(1)
Variant Alleles T/C
Minor Allele C
Minor Allele Frequence 0.185304
Functional Annotation missense_variant; upstream_gene_variant.
Polyphen Annotation: benign(ENST00000614998, ENST00000361923, ENST00000377532, ENST00000613533)
SIFT Annotation: tolerated - low confidence(ENST00000361923, ENST00000377532, ENST00000613533); tolerated(ENST00000614998)
Consequence to Transcript missense_variant(ENST00000614998, ENST00000361923, ENST00000377532, ENST00000613533); upstream_gene_variant(ENST00000451646)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Mansour, H. A.,2009 Single SNP-based analyses: Trends test P-value = 0.421 in BP...... Single SNP-based analyses: Trends test P-value = 0.421 in BPI More... No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
PER3 period circadian clock 3 1p36.23 7(3/4/0)

SNPs in LD with rs2640909 (count: 0) View in gBrowse (chr1:7830057..7830057 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Mansour, H. A.,2009 Single SNP-based analyses:Trends test P-value = 0.031 in SZ Significant association was observed Positive

Overlap with MDD from cross-disorder studies (count: 0)