Gene Report

Approved Symbol	RORA
Symbol Alias	RZRA, ROR1, ROR2, ROR3, NR1F1
Approved Name	RAR-related orphan receptor A
Location	15q21-q22
Position	chr15:60488284-61229319, -1
External Links	HGNC: 10258 Entrez Gene: 6095 Ensembl: ENSG00000069667 UCSC: uc002agv.3
No. of Studies	3 (Positive: 2; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	YES

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Lai, Y. C., 2015	SNP: rs8041381, rs11632600, rs75981965, rs339998, rs2553236, rs13329238, rs17237353, rs1020729, rs1020730, rs12900122, rs8025689, rs9302215, rs1482057, rs11639084, rs12594188, rs10519067, rs11071557, rs11071558, rs922781, rs1963497, rs17270446, rs877228, rs16943117, rs12915776, rs6494227, rs79610262, rs35752305, rs16943172, rs75084363, rs8041466, rs11631432, rs2414686, rs12910281, rs2899664, rs11855147, rs79995443, rs72752802, rs74687025, rs4775350, rs782908, rs76824799, rs4774388, rs34720147, rs11631786	Gene-based association was significant for RORA gene (P = 0.0007).. Our results support for the involvement of RORs genes in the risk of developing BD.	Positive	Comment on Study
Soria, V.,2010	SNP: rs4774370	Significant associations of RORA gene were found in BPD patients.	Positive	Comment on Study
McGrath, C. L.,2009		There was no evidence for association between pediatric bipolar disorder and any RORA SNPs or haplotype blocks after multiple-test correction.	Negative	Comment on Study

Region: chr15:60488284..61229319 View in gBrowse