SNP Report

Basic Info

Name	rs10207288 dbSNP Ensembl
Location	chr2:211676652 - 211676652(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.448882
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000260943, ENST00000342788, ENST00000402597, ENST00000436443, ENST00000484594); non_coding_transcript_variant(ENST00000484594)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Chen, P.,2012	C/T	T	Chi square test: allele P-value = 0.929, OR=0.991; genotype ...... Chi square test: allele P-value = 0.929, OR=0.991; genotype P-value = 0.779, chi square=0.499 for BPAD More...	No significant association was observed in BPAD. No significant association was observed in BPAD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ERBB4	erb-b2 receptor tyrosine kinase 4	2q33.3-q34	2(1/1/0)

SNPs in LD with rs10207288 (count: 20) View in gBrowse (chr2:211665741..211683052 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 20)

rs_ID	Functional Annotation	r²[population]
rs10191972	intron_variant; non_coding_transcript_variant	0.823[CHB]; 0.911[CHD]; 1.0[JPT]
rs13019783	intron_variant; non_coding_transcript_variant	0.823[CHB]; 0.917[CHD]; 1.0[JPT]
rs6705698	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs17413784	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.847[CHB]; 1.0[JPT]
rs12476100	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[JPT]
rs1829615	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs10183757	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs6714941	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs2272024	intron_variant; non_coding_transcript_variant	0.823[CHB]; 0.917[CHD]; 1.0[JPT]
rs3817429	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs6705988	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs11893474	intron_variant; non_coding_transcript_variant	0.847[CHB]; 1.0[JPT]
rs6759039	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs1851168	intron_variant; non_coding_transcript_variant	1.0[JPT]
rs13001867	intron_variant; non_coding_transcript_variant	1.0[CHB]; 1.0[JPT]
rs4423543	intron_variant; non_coding_transcript_variant	1.0[JPT]
rs16846710	intron_variant; non_coding_transcript_variant	1.0[JPT]
rs6725181	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.923[CHD]; 1.0[JPT]
rs13424871	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs11893380	intron_variant; non_coding_transcript_variant	0.846[CHB]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Chen, P.,2012	Chi square test: allele P-value = 0.889, OR=1.014;genotype P-value = 0.889, chi square=0.019 for SCZ	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Chen, P.,2012	Chi square test: allele P-value = 0.578, OR=0.946;genotype P-value = 0.796, chi square=0.455 for MDD	No significant association was observed.	Negative