SNP Report

Basic Info

Name	rs3809646 dbSNP Ensembl
Location	chr16:89720447 - 89720447(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.170527
Functional Annotation	5_prime_UTR_variant; downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000562530); downstream_gene_variant(ENST00000562298, ENST00000562866); intron_variant(ENST00000389386, ENST00000563798); NMD_transcript_variant(ENST00000562530, ENST00000563798); upstream_gene_variant(ENST00000289816, ENST00000443381, ENST00000561536, ENST00000561976, ENST00000563541, ENST00000563983, ENST00000568064, ENST00000568295, ENST00000569426)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Andreassen OA, 2013			Conditional FDR; BD loci given SCZ: P-value=0.000576, FDR=0....... Conditional FDR; BD loci given SCZ: P-value=0.000576, FDR=0.60769, FDR=0.03171 for BD and SCZ More...	This SNP is with conditional FDR<0.05 in schizophrenia given...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More...	Positive

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
VPS9D1-AS1	VPS9D1 antisense RNA 1	16q24.3	Mapped by Literature SNP
ZNF276	zinc finger protein 276	16q24.3	Mapped by Literature SNP
VPS9D1	VPS9 domain containing 1	16q24.3	Mapped by Literature SNP

SNPs in LD with rs3809646 (count: 0) View in gBrowse (chr16:89720447..89720447 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Andreassen OA, 2013	Conditional FDR; BD loci given SCZ: FDR=0.03171 for BD and SCZ	This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'.	Positive

Overlap with MDD from cross-disorder studies (count: 0)