BDgene

SNP Report

Basic Info
Name rs704073 dbSNP Ensembl
Location chr12:89347934 - 89347934(1)
Variant Alleles G/A
Ancestral Allele A
Minor Allele A
Minor Allele Frequence 0.245208
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000279488); downstream_gene_variant(ENST00000308385, ENST00000547140, ENST00000547291, ENST00000548755); upstream_gene_variant(ENST00000611513)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kim, S. H., 2012 (a) C/T chi-square P-value = 0.0624, Permutation P-value = 0.2083, X...... chi-square P-value = 0.0624, Permutation P-value = 0.2083, X2=3.472, OR=2.105; chi-square P-value = 0.038, Permutation P-value = 0.1229, X2=4.3044, OR=3.091 for female subjects, chi-square P-value = 0.8272, Permutation P-value = 0.9992, X2=0.0476, OR=1.149 for male subjects More... showed nominally significant allelic associations with BD, b...... showed nominally significant allelic associations with BD, but not with SPR, in female patients More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
DUSP6 dual specificity phosphatase 6 12q22-q23 5(3/2/0)

SNPs in LD with rs704073 (count: 26) View in gBrowse (chr12:89324319..89383534 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 26)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Kim, S. H., 2012 (a) chi-square P-value = 0.5978, Permutation P-value = 0.9424, X2=0.2783, OR=1.294; chi-square P-value = 0.6115, Permutation P-value = 0.9859, X2=0.2579, OR=1.475 for female subjects, chi-square P-value = 0.8272, Permutation P-value = 0.9993, X2=0.0476, OR=1.149 for male subjects showed nominally significant allelic associations with BD, but not with SPR, in female patients Negative

Overlap with MDD from cross-disorder studies (count: 0)