SNP Report

Basic Info

Name	rs688325 dbSNP Ensembl
Location	chr1:147605490 - 147605490(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.292532
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000234739, ENST00000497938); non_coding_transcript_variant(ENST00000497938)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Li, J.,2011(b)	A/G		Third-Stage Sample: for BPD, allele association P-value = 0....... Third-Stage Sample: for BPD, allele association P-value = 0.14, OR(95%CI)=1.10(0.97-1.23) More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
BCL9	B-cell CLL/lymphoma 9	1q21	1(1/0/0)

SNPs in LD with rs688325 (count: 0) View in gBrowse (chr1:147605490..147605490 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Li, J.,2011(b)	Third-Stage Sample:for SZ, allele association P-value = 0.006, OR(95%CI)=1.19(1.05-1.33);Combined Third-Stage Sample, allele association P-value = 0.000254, OR(98%CI)=1.11(1.05-1.18)	Significant association was observed in SZ.	Positive

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Li, J.,2011(b)	Third-Stage Sample:for MDD, allele association P-value = 0.02, OR(95%CI)=1.16(1.03-1.32)	Significant association was observed in MDD.	Positive