SNP Report
Basic Info
Name |
rs4785714
dbSNP
Ensembl
|
Location |
chr16:89731996 - 89731996(1) |
Variant Alleles |
C/A/T |
Ancestral Allele |
C |
Minor Allele |
A |
Minor Allele Frequence |
0.185703 |
Functional Annotation |
intron_variant; NMD_transcript_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant.
|
Consequence to Transcript |
intron_variant(ENST00000289816, ENST00000443381, ENST00000561536, ENST00000562530, ENST00000563541, ENST00000563983, ENST00000568064, ENST00000568295, ENST00000569426); NMD_transcript_variant(ENST00000562530, ENST00000563541, ENST00000568295); non_coding_transcript_exon_variant(ENST00000564004); non_coding_transcript_variant(ENST00000561536, ENST00000563983, ENST00000564004, ENST00000569426); upstream_gene_variant(ENST00000569582) |
No. of Studies |
1 (Positive: 1; Negative: 0; Trend: 0) |
Source |
Literature |
Overlap with SZ? |
YES
|
Overlap with MDD? |
NO
|
SNP related studies (count: 1)
SNP related genes (count: 1)
Overlap with SZ from cross-disorder studies (count: 1)
Reference |
Statistical Result |
Description |
Result Category |
Andreassen OA, 2013 |
Conditional FDR; SCZ loci given BD: P-value=0.00134, FDR=0.527, FDR=0.034 for SCZ and BD |
To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. |
Positive |
Overlap with MDD from cross-disorder studies (count: 0)