SNP Report

Basic Info

Name	rs769390 dbSNP Ensembl
Location	chr2:170836945 - 170836945(1)
Variant Alleles	A/C
Ancestral Allele	A
Minor Allele	C
Minor Allele Frequence	0.208267
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000344257, ENST00000358196, ENST00000375272, ENST00000414527, ENST00000429023, ENST00000493875, ENST00000625689); NMD_transcript_variant(ENST00000414527, ENST00000493875); non_coding_transcript_variant(ENST00000429023)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Yosifova, A.,2009	A/C		Allelic association: P-value = 0.21 Allelic association: P-value = 0.21	No significant association was observed No significant association was observed	Negative
Lundorf, M. D.,2005	C/A		Fisher's exact test: for BPAD, in Danish sample set, P-value...... Fisher's exact test: for BPAD, in Danish sample set, P-value(allele)=0.084, P-value(genotype)=0.13; in Scottish sample set, P-value(allele)=0.68, P-value(genotype)=0.58 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GAD1	glutamate decarboxylase 1 (brain, 67kDa)	2q31	2(1/1/0)

SNPs in LD with rs769390 (count: 0) View in gBrowse (chr2:170836945..170836945 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Lundorf, M. D.,2005	Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=0.8, P-value(genotype)=0.85	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)