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SNP Report
Basic Info
| Name | rs1573745 dbSNP Ensembl | ||
|---|---|---|---|
| Location | chr22:40844831 - 40844831(1) | ||
| Variant Alleles | G/A | ||
| Ancestral Allele | G | ||
| Minor Allele | A | ||
| Minor Allele Frequence | 0.0838658 | ||
| Functional Annotation | intron_variant; NMD_transcript_variant; splice_region_variant. | ||
| Consequence to Transcript | intron_variant(ENST00000216218, ENST00000411695, ENST00000413424, ENST00000455824, ENST00000620312); NMD_transcript_variant(ENST00000413424, ENST00000455824); splice_region_variant(ENST00000216218, ENST00000411695, ENST00000413424, ENST00000455824, ENST00000620312) | ||
| No. of Studies | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
| Overlap with SZ? | YES | ||
| Overlap with MDD? | NO | ||
SNP related studies (count: 1)
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 22q13.2 | 1(1/0/0) |
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 27)
Overlap with SZ from cross-disorder studies (count: 1)
| Reference | Statistical Result | Description | Result Category |
|---|---|---|---|
| Severinsen, J. E., 2006 (a) | Empirical overall P-value = 0.2879 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.7989 for BPD and SZ in the Case-Control Sample From Scotland | Negative |
Overlap with MDD from cross-disorder studies (count: 0)