SNP Report

Basic Info

Name	rs7175812 dbSNP Ensembl
Location	chr15:92119971 - 92119971(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.114816
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000318445, ENST00000424469, ENST00000553653, ENST00000555549, ENST00000555769); non_coding_transcript_variant(ENST00000553653, ENST00000555549, ENST00000555769)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McAuley, E. Z., 2012	G/A		P-value = 0.036, Empirical P-value = 0.035, OR (95% CI)=1.53...... P-value = 0.036, Empirical P-value = 0.035, OR (95% CI)=1.53 (1.07-2.38) in the Australian bipolar disorder cohort More...	Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. Association with 14 of these SNPs held true when empirical P values were obtained through 10, 000 replicate permutations. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLCO3A1	solute carrier organic anion transporter family, member 3A1	15q26	2(1/1/0)

SNPs in LD with rs7175812 (count: 11) View in gBrowse (chr15:92102141..92119971 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs207952	intron_variant; non_coding_transcript_variant	0.812[TSI]
rs7179547	intron_variant; non_coding_transcript_variant	0.894[CEU]
rs12439582	intron_variant; non_coding_transcript_variant	0.945[CEU]; 0.946[TSI]
rs11631993	intron_variant; non_coding_transcript_variant	0.894[CEU]; 0.853[TSI]
rs11074041	intron_variant; non_coding_transcript_variant	1.0[CEU]
rs12437502	intron_variant; non_coding_transcript_variant	0.894[CEU]; 0.853[TSI]
rs1517618	missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.945[CEU]
rs16974268	intron_variant; non_coding_transcript_variant	0.945[CEU]; 0.946[TSI]
rs207964	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.887[CEU]
rs185950	intron_variant; non_coding_transcript_variant	0.894[CEU]; 0.853[TSI]
rs4984338	intron_variant; non_coding_transcript_variant	0.945[CEU]; 0.897[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
McAuley, E. Z., 2012	P-value > 0.075	Single SNP analysis did not yield significant evidence for association.	Negative

Overlap with MDD from cross-disorder studies (count: 0)