SNP Report

Basic Info

Name	rs4820902 dbSNP Ensembl
Location	chr22:30769737 - 30769737(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.234026
Functional Annotation	intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000332585, ENST00000401475, ENST00000403222, ENST00000407373, ENST00000438716, ENST00000445781, ENST00000446658, ENST00000464341, ENST00000477355); non_coding_transcript_variant(ENST00000464341, ENST00000477355); upstream_gene_variant(ENST00000496367)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Bergen, S. E.,2012		T	logistic regression: P-value > E-05 logistic regression: P-value > E-05	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
OSBP2	oxysterol binding protein 2	22q12.2	1(0/1/0)

SNPs in LD with rs4820902 (count: 1) View in gBrowse (chr22:30743666..30769737 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs5753303		intron_variant	0.958[CEU]; 0.822[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Bergen, S. E.,2012	logistic regression:for SZ new sample, OR=0.78, P-value = 9.98E-06	No significant association was observed in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 0)