Gene Report

Basic Info
Approved Symbol ZBED4
Symbol Alias KIAA0637
Approved Name zinc finger, BED-type containing 4
Location 22q13.33
Position chr22:49853842-49890078, 1
External Links HGNC: 20721
Entrez Gene: 9889
Ensembl: ENSG00000100426
UCSC: uc003bix.2
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Nyegaard, M., 2010 SNP: rs3788731, rs4624, rs5769750, rs5770755, rs6009917, rs910799 Due to highLD in the region harboring BRD1, we included SNPs located within the ZBED4 gene in this replication analysis. Analysis of genotyped SNPs as well as imputed genotypes showed the strongest association with markers in BRD1. However, due to the high LD we cannot completely rule out ZBED4 as a positional candidate gene for SZ and BPD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 7)

GO terms by PBA (count: 2)

GO terms by database search (count: 5)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 47)

Literature-origin SNPs (count: 6)

LD-proxies (count: 41)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

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Region: chr22:49853842..49890078 View in gBrowse
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