BDgene

SNP Report

Basic Info
Name rs2675968 dbSNP Ensembl
Location chr2:232871534 - 232871534(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.287141
Functional Annotation downstream_gene_variant; intron_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000448993); intron_variant(ENST00000331342, ENST00000409230, ENST00000409533); upstream_gene_variant(ENST00000449331, ENST00000467665, ENST00000476690, ENST00000481155)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Andreassen OA, 2013 Conditional FDR; SCZ loci given BD: FDR=0.021 for SCZ and BD Conditional FDR; SCZ loci given BD: FDR=0.021 for SCZ and BD To estimate the number of independent loci, we 'pruned' the ...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.19. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
C2orf82 chromosome 2 open reading frame 82 2q37.1 Mapped by Literature SNP

SNPs in LD with rs2675968 (count: 0) View in gBrowse (chr2:232871534..232871534 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Andreassen OA, 2013 Conditional FDR; SCZ loci given BD: P-value=0.0000564, FDR=0.143, FDR=0.021 for SCZ and BD To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.19. Positive

Overlap with MDD from cross-disorder studies (count: 0)