Gene Report

Basic Info
Approved Symbol SGCG
Previous Symbol DMDA1, MAM, LGMD2C
Symbol Alias SCARMD2, DAGA4, SCG3, DMDA, TYPE, A4, MGC130048
Approved Name sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
Previous Name sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)
Name Alias Maghrebian myopathy (autosomal recessive), "35kD dystrophin-associated glycoprotein", "limb girdle muscular dystrophy 2C (Duchenne-like muscular dystrophy, autosomal recessive)", "gamma sarcoglycan"
Location 13q12-q13
Position chr13:23180952-23325165, 1
External Links HGNC: 10809
Entrez Gene: 6445
Ensembl: ENSG00000102683
UCSC: uc001uom.2
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Bergen, S. E.,2012 SNP: rs1409497 No significant association was observed in BD. Negative Comment on Study
Smith, E. N.,2011 SNP: rs4770394 No significant association of this gene was observed in BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 12)

GO terms by PBA (count: 2)

GO terms by database search (count: 10)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 4)

Related other genetic factors
Gene related SNPs (count: 5)

Literature-origin SNPs (count: 2)

LD-proxies (count: 3)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr13:23180952..23325165 View in gBrowse
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