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SNP Report
Name | rs2284178 dbSNP Ensembl | ||
---|---|---|---|
Location | chrCHR_HSCHR6_MHC_SSTO_CTG1:31455062 - 31455062(1) | ||
Variant Alleles | C/T | ||
Ancestral Allele | C | ||
Minor Allele | T | ||
Minor Allele Frequence | 0.46905 | ||
Functional Annotation | downstream_gene_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant. | ||
Consequence to Transcript | downstream_gene_variant(ENST00000460889); intron_variant(ENST00000467369); non_coding_transcript_exon_variant(ENST00000414046, ENST00000541196); non_coding_transcript_variant(ENST00000414046, ENST00000467369, ENST00000541196); upstream_gene_variant(ENST00000440087, ENST00000419355, ENST00000438873, ENST00000419355, ENST00000438873, ENST00000455463, ENST00000457127, ENST00000455463, ENST00000457127, ENST00000447631, ENST00000423496, ENST00000423496) | ||
No. of Studies | 1 (Positive: 1; Negative: 0; Trend: 0) | ||
Source | Literature | ||
Overlap with SZ? | YES | ||
Overlap with MDD? | NO |
SNPs in LD with rs2284178 (count: 0) View in gBrowse (chrCHR_HSCHR6_MHC_SSTO_CTG1:31455062..31455062 )
Reference | Statistical Result | Description | Result Category |
---|---|---|---|
Andreassen OA, 2013 | Conditional FDR; SCZ loci given BD: P-value=0.000331, FDR=0.316, FDR=0.036 for SCZ and BD | To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. | Positive |