Gene Report

Basic Info
Approved Symbol HNF4A
Previous Symbol TCF14, MODY, MODY1
Symbol Alias NR2A1, HNF4
Approved Name hepatocyte nuclear factor 4, alpha
Location 20q13.12
Position chr20:44355700-44434596, 1
External Links HGNC: 5024
Entrez Gene: 3172
Ensembl: ENSG00000101076
UCSC: uc002xma.4
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Kajio, Y., 2014 SNP: rs4812829 SNPs in SLC30A8 (rs3802177, Puncorrected=0.042) and HNF4A(rs4812829, Puncorrected=0.0082), which showed the opposite direction of effect. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 44)

GO terms by PBA (count: 7)

GO terms by database search (count: 37)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 29)

Related other genetic factors
Gene related SNPs (count: 6)

Literature-origin SNPs (count: 1)

LD-proxies (count: 5)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr20:44355700..44434596 View in gBrowse
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