Gene Report

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Basic Info

Approved Symbol	C15orf32
Symbol Alias	FLJ32831
Approved Name	chromosome 15 open reading frame 32
Location	15q26.1
Position	chr15:92471654-92501117, 1
External Links	HGNC: 26549 Entrez Gene: 145858 Ensembl: ENSG00000183643 UCSC: uc002brc.1
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
McAuley, E. Z., 2012	SNP: rs12441404, rs13380006, rs1455773	Nominally significant association (P < 0.05) was found with 3 SNPs with BD.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 0)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 14)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs8040009	chr15:92501109 - 92501109(1)	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	1(0/0/1)
rs13380006	chr15:92472898 - 92472898(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1(1/0/0)
rs1455773	chr15:92472197 - 92472197(1)	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	1(1/0/0)
rs12441404	chr15:92473682 - 92473682(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1(1/0/0)
rs7174854	chr15:92500746 - 92500746(1)	non_coding_transcript_exon_variant; non_coding_transcript_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs737414	chr15:92502812 - 92502812(1)	downstream_gene_variant
rs1869774	chr15:92466947 - 92466947(1)	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant
rs12708594	chr15:92481334 - 92481334(1)	intron_variant; non_coding_transcript_variant
rs7163161	chr15:92479255 - 92479255(1)	intron_variant; non_coding_transcript_variant
rs897466	chr15:92471253 - 92471253(1)	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant
rs11634493	chr15:92469865 - 92469865(1)	downstream_gene_variant; upstream_gene_variant
rs17600420	chr15:92467905 - 92467905(1)	3_prime_UTR_variant; downstream_gene_variant; upstream_gene_variant
rs1455774	chr15:92472091 - 92472091(1)	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant
rs2279447	chr15:92470330 - 92470330(1)	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
15q26.1	chr15:88500000-93800000	1 (0/0/1)
15q25-26	chr15:78000000-101991189	1 (1/0/0)
15q26	chr15:88500000-101991189	1 (0/1/0)
Chr 15	chr15:0-101991189	2 (0/2/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Reference	Description	Result Category
22693595	No significant association was reported in this study.	Negative

Gene relationship with MDD

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Region: chr15:92471654..92501117 View in gBrowse