Gene Report

Basic Info
Approved Symbol ANO2
Previous Symbol C12orf3, TMEM16B
Approved Name anoctamin 2, calcium activated chloride channel
Previous Name chromosome 12 open reading frame 3, "transmembrane protein 16B", "anoctamin 2"
Name Alias transmembrane protein 16B (eight membrane-spanning domains)
Location 12p13.3
Position chr12:5531869-5946232, -1
External Links HGNC: 1183
Entrez Gene: 57101
Ensembl: ENSG00000047617
UCSC: uc031yre.1
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Huang, J.,2010 SNP: rs4140862 No significant association of this gene was observed in BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 10)

GO terms by PBA (count: 1)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

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Region: chr12:5531869..5946232 View in gBrowse
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