SNP Report

Basic Info

Name	rs27072 dbSNP Ensembl
Location	chrCHR_HSCHR5_3_CTG1:1437900 - 1437900(-1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.205072
Functional Annotation	3_prime_UTR_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; intron_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000270349); non_coding_transcript_exon_variant(ENST00000512002); non_coding_transcript_variant(ENST00000512002); intron_variant(ENST00000621716)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pinsonneault, J. K.,2011			Stanley sample: allele, X² P-value = 0.03, Fisher...... Stanley sample: allele, X² P-value = 0.03, Fisher's exact P-value = 0.04, OR=2.19, 95%CI=1.0-4.3 for BD; X² P-value = 0.91, Fisher's exact P-value = 1OR=1.05 for BD; U. of Bari sample: allele, X² P-value = 0.11, Fisher's exact P-value = 0.12, OR=0.77, 95%CI=0.56-1.06 for BD; X² P-value = , Fisher's exact P-value = OR= for BD More...	Significant association was found . Significant association was found .	Positive
Mick, E., 2008		T	TDT X²(df=1)=2.03, P-value = 0.18, OR (95% CI)=1....... TDT X²(df=1)=2.03, P-value = 0.18, OR (95% CI)=1.44(0.97-2.14) More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	5p15.3	11(5/6/0)

SNPs in LD with rs27072 (count: 0) View in gBrowse (chrCHR_HSCHR5_3_CTG1:1437900..1437900 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Pinsonneault, J. K.,2011	Stanley sample:allele, X² P-value = 0.91, Fisher's exact P-value = 1OR=1.05;U. of Bari sample X² P-value = 0.69 for SZ	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)