SNP Report

Basic Info

Name	rs6986716 dbSNP Ensembl
Location	chr8:32390223 - 32390223(1)
Variant Alleles	A/C
Ancestral Allele	C
Minor Allele	A
Minor Allele Frequence	0.36262
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000518104, ENST00000519301, ENST00000520407, ENST00000523534, ENST00000631040)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Thomson, P. A., 2007			Individual P-value = 0.3505 for BP, Individual P-value = 0.5...... Individual P-value = 0.3505 for BP, Individual P-value = 0.5832 for SCZ and BP More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRG1	neuregulin 1	8p12	15(10/5/0)

SNPs in LD with rs6986716 (count: 4) View in gBrowse (chr8:32390223..32409719 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs10102991	intron_variant	1.0[CEU]
rs28392732	intron_variant	0.93[CEU]
rs11985501	intron_variant	1.0[CEU]
rs4733119	intron_variant	0.93[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A., 2007	Individual P-value = 0.991 for SCZ , Individual P-value = 0.5832 for SCZ and BP		Negative

Overlap with MDD from cross-disorder studies (count: 0)