SNP Report

Basic Info

Name	rs6900617 dbSNP Ensembl
Location	chr6:37684410 - 37684410(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.163738
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000434837, ENST00000505425, ENST00000515437)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Li, J.,2011(a)	A/G		Single SNP analyses: allele, P-value = 0.2115, OR[95%CI]=0.9...... Single SNP analyses: allele, P-value = 0.2115, OR[95%CI]=0.9241[0.8164, 1.0459], genotype, P-value = 0.2021 for BP More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	6p21	1(1/0/0)

SNPs in LD with rs6900617 (count: 7) View in gBrowse (chr6:37681909..37702601 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs6933764	upstream_gene_variant	0.852[CHB]; 0.853[CHD]; 0.853[JPT]
rs6936811	intron_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs13195437	intron_variant	1.0[CHB]; 0.943[JPT]
rs9394451	intron_variant	1.0[CHB]; 1.0[JPT]
rs9380699	intron_variant	1.0[CHB]; 1.0[JPT]
rs9357252	upstream_gene_variant	0.852[CHB]; 0.829[CHD]; 0.853[JPT]
rs9394452	intron_variant	1.0[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Li, J.,2011(a)	Single SNP analyses:allele, P-value = 0.4061, OR[95%CI]=1.0553[0.9295, 1.1981], genotype, P-value = 0.3642 for SZ	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Li, J.,2011(a)	Single SNP analyses:allele, P-value = 0.1106, OR[95%CI]=1.1083[0.9768, 1.2575], genotype, P-value = 0.2453 for MDD	No significant association was observed.	Negative