Gene Report

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Basic Info

Approved Symbol	SURF6
Symbol Alias	FLJ30322, RRP14
Approved Name	surfeit 6
Name Alias	surfeit locus protein 6
Location	9q33-q34
Position	chr9:133328774-133336398, -1
External Links	HGNC: 11478 Entrez Gene: 6838 Ensembl: ENSG00000148296 UCSC: uc004cdb.5
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Bergen, S. E.,2012	SNP: rs9411508	No significant association was observed in BD.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0003677	DNA binding	molecular function	ISS	83

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0001652	granular component	cellular component	ISS	1
GO:0042254	ribosome biogenesis	biological process	IEA	3
GO:0005730	nucleolus	cellular component	TAS[10675619]	28
GO:0003723	RNA binding	molecular function	ISS	14
GO:0005654	nucleoplasm	cellular component	IEA	163
GO:0044822	poly(A) RNA binding	molecular function	IDA[22658674]	44

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs9411508	chrCHR_HG2030_PATCH:133320932 - 133320932(1)	downstream_gene_variant	1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 9	chr9:0-138394717	3 (0/3/0)
9q33.3-34.3	chr9:123100000-138394717	1 (0/1/0)
9q34	chr9:127500000-138394717	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Reference	Description	Result Category
22688191	No significant association was observed in SZ.	Negative

Gene relationship with MDD

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Region: chr9:133328774..133336398 View in gBrowse