Gene Report

Basic Info
Approved Symbol LMAN2L
Symbol Alias DKFZp564L2423, VIPL
Approved Name lectin, mannose-binding 2-like
Location 2q11.1
Position chr2:96705929-96740064, -1
External Links HGNC: 19263
Entrez Gene: 81562
Ensembl: ENSG00000114988
UCSC: uc002swv.3
No. of Studies 2 (Positive: 2; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Chen, D. T.,2011 SNP: rs2271893, rs6746896 The results suggest novel association findings near the gene. Positive Comment on Study
Lim C.H., 2014 SNP: rs6746896, rs2271893 A positive association between LMAN2L (rs6746896) and risk of both BPD and SZ in a pooled population (P-value=0.009 and 0.001, respectively). Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 10)

GO terms by PBA (count: 1)

GO terms by database search (count: 9)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 2)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr2:96705929..96740064 View in gBrowse
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