BDgene

SNP Report

Basic Info
Name rs3131296 dbSNP Ensembl
Location chrCHR_HSCHR6_MHC_SSTO_CTG1:32212897 - 32212897(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.0784744
Functional Annotation intron_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000375023); upstream_gene_variant(ENST00000474612, ENST00000425600, ENST00000466682, ENST00000437843, ENST00000485109, ENST00000454571, ENST00000471956, ENST00000439349, ENST00000465833, ENST00000383264, ENST00000476219, ENST00000457094, ENST00000495284)
No. of Studies 2 (Positive: 1; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Williams, H. J.,2011 Armitage trend test: P-value = 0.01, OR=1.14, 95%CI=(1.02-1....... Armitage trend test: P-value = 0.01, OR=1.14, 95%CI=(1.02-1.25) More... Significant association was found. Significant association was found. Positive
Steinberg, S.,2012 G Association results in bipolar disorder follow-up samples(7,...... Association results in bipolar disorder follow-up samples(7,333 cases; 43,779 controls):OR(95% CI) = 1.02 (0.96, 1.09),P-value = 0.46 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
NOTCH4 notch 4 6p21.3 2(0/2/0)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Steinberg, S.,2012 Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.15 (1.08, 1.21),P-value = 1.4 x 10-6 Suggestive association was found. Trend

Overlap with MDD from cross-disorder studies (count: 0)