SNP Report

Basic Info

Name	rs28365859 dbSNP Ensembl
Location	chrCHR_HSCHR17_2_CTG2:1303263 - 1303263(1)
Variant Alleles	C/G
Ancestral Allele	C
Minor Allele	G
Minor Allele Frequence	0.38758
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000264335, ENST00000469398, ENST00000486241, ENST00000489287, ENST00000498643, ENST00000571732, ENST00000572108, ENST00000573026, ENST00000573196, ENST00000575977, ENST00000576854, ENST00000616643, ENST00000626999, ENST00000627099, ENST00000627231, ENST00000628106, ENST00000628981, ENST00000630045, ENST00000630606, ENST00000630699, ENST00000630936, ENST00000631243)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Liu, J,2011(b)			For BD: allele, OR[95%CI]=1.04[0.91-1.18], P-value = 0.5967,...... For BD: allele, OR[95%CI]=1.04[0.91-1.18], P-value = 0.5967, P-permutation=1; genotype, P-value = 0.4869, P-permutation=1 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon	17p13.3	1(0/1/0)

SNPs in LD with rs28365859 (count: 0) View in gBrowse (chrCHR_HSCHR17_2_CTG2:1303263..1303263 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Liu, J,2011(b)	For SZ:allele, OR[95%CI]=1.04[0.91-1.19], P-value = 0.5431, P-permutation=1;genotype, P-value = 0.18954, P-permutation=0.9176	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Liu, J,2011(b)	For MDD:allele, OR[95%CI]=1.09[0.96-1.24], P-value = 0.18902, P-permutation=0.925;genotype, P-value = 0.36552, P-permutation=0.9955	No significant association was observed.	Negative