SNP Report
Basic Info
| Name |
rs1541187
dbSNP
Ensembl
|
| Location |
chr1:147579693 - 147579693(1) |
| Variant Alleles |
C/T |
| Ancestral Allele |
C |
| Minor Allele |
T |
| Minor Allele Frequence |
0.158546 |
| Functional Annotation |
intron_variant.
|
| Consequence to Transcript |
intron_variant(ENST00000234739) |
| No. of Studies |
1 (Positive: 0; Negative: 1; Trend: 0) |
| Source |
Literature |
| Overlap with SZ? |
YES
|
|---|
| Overlap with MDD? |
YES
|
|---|
SNP related studies (count: 1)
SNP related genes (count: 1)
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 2)
| rs_ID |
Literature-origin SNPs with LD |
Functional Annotation |
r2[population] |
|
rs1546161
|
|
intron_variant |
0.888[CHB]
|
|
rs11240081
|
|
intron_variant |
1.0[CHB]
|
Overlap with SZ from cross-disorder studies (count: 1)
| Reference |
Statistical Result |
Description |
Result Category |
| Li, J.,2011(b) |
Third-Stage Sample:for SZ, allele association P-value = 0.15, OR(95%CI)=1.16(0.95-1.43);Combined Third-Stage Sample, allele association P-value = 0.24, OR(98%CI)=1.06(0.97-1.17) |
No significant association was observed. |
Negative |
Overlap with MDD from cross-disorder studies (count: 1)
| Reference |
Statistical Result |
Description |
Result Category |
| Li, J.,2011(b) |
Third-Stage Sample:for MDD, allele association P-value = 0.04, OR(95%CI)=1.23(1.01-1.52) |
Significant association was observed in MDD. |
Positive
|
