SNP Report

Basic Info

Name	rs7126303 dbSNP Ensembl
Location	chr11:13348988 - 13348988(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.373602
Functional Annotation	intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000389707, ENST00000401424, ENST00000403290, ENST00000403510, ENST00000480685, ENST00000482049, ENST00000527998, ENST00000529050, ENST00000529388, ENST00000529825, ENST00000530357, ENST00000531665, ENST00000533520, ENST00000534544); non_coding_transcript_variant(ENST00000480685); upstream_gene_variant(ENST00000410230, ENST00000485918)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Mansour, H. A.,2009	A/G		Single SNP-based analyses: Trends test P-value = 0.04 in BPI Single SNP-based analyses: Trends test P-value = 0.04 in BPI	Significant association was observed Significant association was observed	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	11p15	7(5/2/0)
RN7SKP151	RNA, 7SK small nuclear pseudogene 151	11p15.2	Mapped by Literature SNP

SNPs in LD with rs7126303 (count: 2) View in gBrowse (chr11:13341268..13348988 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs12421530		intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.961[CEU]; 0.95[TSI]
rs7937060		intron_variant; non_coding_transcript_variant	0.961[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Mansour, H. A.,2009	Single SNP-based analyses:Trends test P-value = 0.738 in SZ	No significant association was observed	Negative

Overlap with MDD from cross-disorder studies (count: 0)