Gene Report

Basic Info
Approved Symbol PIK3C2A
Symbol Alias PI3K-C2alpha
Approved Name phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
Previous Name phosphoinositide-3-kinase, class 2, alpha polypeptide
Location 11p15.5-p14
Position chr11:17077730-17207983, -1
External Links HGNC: 8971
Entrez Gene: 5286
Ensembl: ENSG00000011405
UCSC: uc001mmq.5
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Ruderfer, D. M., 2013 SNP: rs4356203 The association near PIK3C2A (chr11: 17023194-17381287) is novel. The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 29)

GO terms by PBA (count: 3)

GO terms by database search (count: 26)

Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 1)

KEGG pathways by database search (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr11:17077730..17207983 View in gBrowse
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