SNP Report

Basic Info

Name	rs984402 dbSNP Ensembl
Location	chr1:240952383 - 240952383(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.308307
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000348120, ENST00000366563, ENST00000366564, ENST00000366565)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Bergen, S. E.,2012		T	logistic regression: P-value > E-05 logistic regression: P-value > E-05	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
RGS7	regulator of G-protein signaling 7	1q43	1(0/1/0)

SNPs in LD with rs984402 (count: 8) View in gBrowse (chr1:240949874..240968716 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs12119557	intron_variant	0.87[CEU]
rs12072679	intron_variant	1.0[CEU]
rs3912106	intron_variant	0.852[TSI]
rs3912107	intron_variant	0.956[CEU]; 0.955[TSI]
rs10802916	intron_variant	0.852[TSI]
rs12143076	intron_variant	0.952[CEU]
rs12132113	intron_variant	0.956[CEU]
rs12731839	intron_variant	0.956[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Bergen, S. E.,2012	logistic regression:for SZ full sample, OR=0.79, P-value = 3.43E-07	No significant association was observed in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 0)