SNP Report

Basic Info

Name	rs11122396 dbSNP Ensembl
Location	chr1:232039522 - 232039522(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.096246
Functional Annotation	3_prime_UTR_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000366637, ENST00000439617, ENST00000620189, ENST00000622252)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Thomson, P. A.,2005(a)			Single-Marker Analysis: allele frequency, for BP, P-value = ...... Single-Marker Analysis: allele frequency, for BP, P-value = 0.45 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TSNAX	translin-associated factor X	1q42.2	4(3/1/0)
DISC1	disrupted in schizophrenia 1	1q42.1	18(10/7/1)

SNPs in LD with rs11122396 (count: 19) View in gBrowse (chr1:232035783..232055966 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs13374539		1.0[CEU]
rs16856330	downstream_gene_variant	1.0[CEU]
rs16856342	downstream_gene_variant	1.0[CEU]
rs16856349	downstream_gene_variant	1.0[CEU]
rs16856346	downstream_gene_variant	1.0[CEU]
rs16856363	downstream_gene_variant	1.0[CEU]
rs16856351	downstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs12403689		1.0[CEU]
rs16856336	downstream_gene_variant	1.0[CEU]
rs16856375		1.0[CEU]
rs16856305	intron_variant	1.0[CEU]
rs16856377		1.0[CEU]
rs16856357	downstream_gene_variant	1.0[CEU]
rs16856339	downstream_gene_variant	1.0[CEU]
rs16856354	downstream_gene_variant	1.0[CEU]
rs16856372		1.0[CEU]
rs16856365	downstream_gene_variant	1.0[CEU]
rs11122398	downstream_gene_variant	1.0[CEU]; 1.0[TSI]
rs16856355	downstream_gene_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A.,2005(a)	Single-Marker Analysis:allele frequency, for SZ, P-value = 0.51	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)