BDgene

SNP Report

Basic Info
Name rs13380006 dbSNP Ensembl
Location chr15:92472898 - 92472898(1)
Variant Alleles C/T
Ancestral Allele G
Minor Allele T
Minor Allele Frequence 0.41853
Functional Annotation downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000268164); intron_variant(ENST00000556865, ENST00000624458); non_coding_transcript_variant(ENST00000556865, ENST00000624458); upstream_gene_variant(ENST00000554440)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
McAuley, E. Z., 2012 A/G P-value = 0.034, Empirical P-value = 0.042, OR (95% CI)=1.41...... P-value = 0.034, Empirical P-value = 0.042, OR (95% CI)=1.41 (0.97-1.82) in the Australian bipolar disorder cohort More... Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. Association with 14 of these SNPs held true when empirical P values were obtained through 10, 000 replicate permutations. More... Positive

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 15q26 2(2/0/0)
C15orf32 chromosome 15 open reading frame 32 15q26.1 1(1/0/0)

SNPs in LD with rs13380006 (count: 3) View in gBrowse (chr15:92467905..92472898 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 3)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
McAuley, E. Z., 2012 P-value > 0.075 Single SNP analysis did not yield significant evidence for association. Negative

Overlap with MDD from cross-disorder studies (count: 0)